September 2018 Vol XLII Issue 9

Previous Month


NUTRITION ISSUES IN GASTROENTEROLOGY, SERIES #179

Pragmatic Management of Nutrition in Severe Acute Pancreatitis

Dushant Uppal

Severe acute pancreatitis (SAP) is a clinically debilitating condition with significant morbidity and mortality that requires attention to optimal supportive management. In this article we discuss nutrition management options, which are critical to supportive management, with appropriate route and timing of nutritional support paramount to optimal outcomes.



FRONTIERS IN ENDOSCOPY, SERIES #45

Endoscopic Management of Zenker's Diverticulum

Bilal Aslam, Moamen Gabr

Zenker's diverticulum (ZD) is a pharyngeoesophageal pulsion diverticulum which presents in the elderly and contributes to morbidity due to dysphagia and pulmonary aspiration. Open surgery and rigid endoscopy have previously been the primary modalities for therapy, however with a favorable safety profile and similar success rates, flexible endoscopy has become an emerging therapeutic modality in the treatment of ZD. This review seeks to highlight endoscopic techniques and tools in the management of ZD.



DISPATCHES FROM THE GUILD CONFERENCE, SERIES #16

Advances in Barrett's Esophagus

Alina Wong, Seth A. Gross

Barrett's esophagus is the strongest risk factor for esophageal adenocarcinoma making evaluation for Barrett's esophagus of utmost importance. Currently screening and surveillance are accomplished with regular white light endoscopy; however, new advances in both population screening and surveillance are being developed. This review will cover selecting the appropriate patient population for Barrett's esophagus screening, available and upcoming technologies for screening and surveillance, and lastly treatment of Barrett's esophagus.



A SPECIAL ARTICLE

Combining Women's Cancer Screening Examinations Shows A Positive Impact On Colorectal Cancer Screening Rates

Marianne T. Ritchie, Apeksha Shah, Bilal A. Asif

Colorectal cancer (CRC) is the 3rd most common cancer among women. In the article we present PINK PLUSTM, an innovative program combining three women's screenings in one visit; mammogram, gynecology exam (GYN) and pre-colonoscopy visit (GI). PINK PLUSTM is a flexible and convenient program demonstrating a high rate of compliance with colonoscopy, which could serve as a national template aimed at increasing adherence to all women's cancer screenings, especially in underserved communities, by combining these life-saving screenings into one visit.



A SPECIAL ARTICLE

Food Additives, the Gut Microbiota, and Inflammatory Bowel Disease:Interpreting the Interplay

David Valadez, Mazyar Malakouti, Tisha Lunsford

The interaction between diet, gut microbiota, and inflammatory bowel disease is an immense process with many complex mechanisms. Food additives are one component of the human diet that face intense scrutiny by society, governing bodies, and science. Here, we review how certain food additives may influence the pathogenesis of IBD, with an emphasis on how food additives affect mechanisms of the gut microbiota.



A CASE REPORT

Autoimmune Enteropathy: An Uncommon Presentation

Alan Naim, Kaivan Salehpour, Camron Kiafar



Departments Section


Medical Bulletin Board

CRH MEDICAL CORPORATION Withstanding GI Reimbursement Pressures

Join CRH Medical Corporation to learn more about the ancillary opportunities available to gastroenterologists at the ACG Annual Meeting 2018 on Monday, October 8 at 12:45 pm in the ACG Product Theater. Speakers Jay Kreger, President of CRH Anesthesia, and Dr. Mitchel Guttenplan, Medical Director for CRH Medical Corporation, discuss. Lunch will be provided and your attendance enters you in a draw to win an iPad Pro.



NEW PHASE 3 DATA SHOW INVESTIGATIONAL SUBCUTANEOUS FORMULATION OF VEDOLIZUMAB MEETS PRIMARY ENDPOINT IN ACHIEVING CLINICAL REMISSION AT WEEK 52 IN PATIENTS WITH MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS

Osaka, Japan - Takeda Pharmaceutical Company Limited [TSE:4502] (Takeda) announced top-line results from the VISIBLE 1 clinical trial evaluating the efficacy and safety of an investigational subcutaneous (SC) formulation of vedolizumab for maintenance therapy in adult patients with moderately to severely active ulcerative colitis (UC) who achieved clinical response at week 6 following two doses of open-label vedolizumab intravenous (IV) induction therapy. In the primary endpoint of the trial, a statistically significant proportion of patients receiving vedolizumab SC beginning at week 6 and every two weeks following achieved clinical remission at week 52 compared to placebo.



COMPULINK LAUNCHES ADVANTAGE SMART PRACTICE™ SUITE OF ARTIFICIAL INTELLIGENCE SOLUTIONS

Newbury Park, CA Compulink Healthcare Solutions, a nationally recognized leader of specialty-specific EHR and Practice Management solutions announced the rollout of new artificial intelligence (AI)-enabled features in a release its calling Advantage SMART Practice.



From the Literature

Natural Course of Eosinophilic Esophagitis

To investigate the natural course of EoE and to evaluate the association between undiagnosed disease and the occurrence of complications over two decades in a large cohort, retrospective analysis of charts of patients diagnosed with EoE between 1996 and 2015 was carried out, collecting information from 15 hospitals throughout the Netherlands. Histologic, clinical, and endoscopic characteristics were identified and stratified by age and diagnostic study.



Evaluation of Time-Dependency of Adalimumab Immunogenicity and Drug Concentrations

Evaluation of Time-Dependency of Adalimumab Immunogenicity and Drug Concentrations



Aspirin Chemoprevention Against Gastric Cancer

To confirm the dose-response relationship of aspirin usage and gastric cancer and to estimate the cumulative dose threshold of aspirin to achieve protective effects against gastric cancer in the general population, 461,489 individuals in a population-based, longitudinal cohort provided by the National Health Insurance Services in the Republic of Korea were observed from 2007 to 2012 to identify gastric cancer incident cases.



Complete Resection of Small Colorectal Polyps

To compare the complete resection rate of hot snare polypectomy (HSP) with that of endoscopic mucosal resection EMR for small, sessile or flat polyps, patients with 5- to 9-mm non-pedunculated colorectal polyps were prospectively randomized for the HSP or EMR group.



From the Pediatric Literature

Fecal Calprotectin Testing in the Primary Care Setting

Fecal calprotectin (FC) is a protein released by neutrophils, and measurement of FC via an ELISA test is used to test for gastrointestinal inflammation, as increased FC levels are associated with disorders such as inflammatory bowel disease (IBD). Gastroenterologists routinely use this test, but utilization of FC testing by primary care physicians for determining a diagnosis in children is unknown.



Esophageal Atresia:Does Fundoplication Work?

Esophageal atresia (EA) is associated with significant morbidity in children, and fundoplication often is performed in patients with EA when complications from gastroesophageal reflux disease (GERD) cannot be controlled with medical management. However, it is unclear if the pathophysiology of EA affects the efficacy of a fundoplication. The authors of this study identified all pediatric patients with EA who had undergone fundoplication and compared this group with all other patient types who had undergone fundoplication at a tertiary children's hospital in Australia over a 20-year period (1994-2013).



Meetings Calendar

September 24-28, 2018, Malnutrition Awareness Week 2018
October 5-10, 2018 American College of Gastroenterology 2018
December 13-15, 2018 Advances in Inflammatory Bowel Diseases - Multidisciplinary Approaches to IBD Patient-Centered Care